Effects of curcumin on hippocampal Bax and Bcl-2 expression and cognitive function of a rat model of

• 作 者: Yunliang Wang Honglei Yin Jiyu
• 机 构: DepartmentofNeurology,DepartmentofNeurology,FirstHospitalAffiliatedtoChongqingMedicalUniversity
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2011年24期
• 关键词: 阿尔茨海默氏症 大鼠模型 认知功能 姜黄素 BAX 海马 老鼠 MORRIS水迷宫 curcumin Alzheimer＇s disease Bax Bcl-2
• 基金项目: Supported by： the National Natural Science Foundation of China, No. 30770762,Acknowledgments： We thank Lingyun Shi and Jiaming Luo, Pharmacology Laboratory of Chongqing Medical University, for technic

We tested the effects of curcumin treatment on a rat model of Alzheimer's disease induced by beta-amlyoid (Aβ1-40) expression. We investigated alterations in the expression of the apoptosis-related genes Bax and Bcl-2 in the hippocampus, as well as ch