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为了探讨乙肝病毒携带产妇母乳喂养的安全性问题，我们收集了72例HBSAg阳性产妇的初乳及其新生儿的静脉血，检测其乙肝病毒标志物和HBVDNA。发现HBeAg阳性产妇和HBeAg阴性产妇初乳的乙肝标志物阳性率分别为71％和45％，其新生儿的宫内感染率分别是29％和16％。结论：HBeAg阳性产妇的乳汁排毒率高，传染性强，不宜哺乳。已发生宫内感染的新生儿母乳喂养利大于弊。尚未感染的新生儿是否喂养母乳要根据母亲乳汁的排毒情况而定。
In order to investigate the safety of hepatitis B virus-carrying mothers breastfeeding, we collected colostrum of 72 HBSAg-positive mothers and the blood of their neonate to detect their hepatitis B virus markers and HBVDNA. The positive rates of hepatitis B markers in HBeAg-positive and HBeAg-negative maternal colostrums were 71% and 45%, respectively. The neonatal intrauterine infection rates were 29% and 16%, respectively. Conclusion: HBeAg-positive maternal milk detoxification rate is high, contagious, not lactating. Newborns with intrauterine infection have more advantages than breastfeeding. Breastfeeding of an uninfected newborn child depends on the detoxification of the mother’s milk.