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本文分析了22例特发性肺间质纤维化(IPF)、40例肺结节病(Sarc)和9例胶原病性肺炎(IP—CVD)的肺功能变化。IPF、IP—CVD肺功能改变较为明显,主要表现为严重的弥散功能障碍和限制性通气功能障碍。Sarc组近半数肺功能正常,其余主要为阻塞性通气功能障碍,限制性和弥散性肺功能障碍的程度较IPF和IP—CVD组明显为轻。Sarc三期间肺功能无明显差异。三组肺功能下降最为显著的是DLco,其次是FEV_1,FVC和FRC等,提出这些指标对间质性肺疾病可能有辅助诊断价值,但需结合其它检查才能确诊。
This article analyzed the changes in lung function in 22 patients with idiopathic pulmonary fibrosis (IPF), 40 patients with pulmonary sarcoidosis (Sarc), and 9 patients with collagen-induced pneumonia (IP-CVD). IPF, IP-CVD lung function changes more obvious, mainly for the performance of diffuse dysfunction and restrictive ventilation dysfunction. Nearly half of the Sarc group had normal pulmonary function, and the rest were mainly obstructive ventilatory dysfunction and restrictive and diffuse pulmonary dysfunction were significantly less severe than IPF and IP-CVD groups. Sarc three lung function no significant difference. The most significant decrease in lung function in the three groups was DLco, followed by FEV_1, FVC and FRC, suggesting that these indicators may have diagnostic value for interstitial lung disease but need to be combined with other tests to confirm the diagnosis.