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目的探讨锯齿状腺瘤(SA)内镜下表现和病理学特征。方法回顾分析滨州医学院附属医院2000年1月～2008年5月检出的大肠息肉病例,了解SA的检出率、内镜形态和病理学特征。结果8 726例肠镜检查共检出大肠息肉1 062例(1 457枚),检出率为12.17%,其中SA 32例(60枚),检出率为0.37%,占息肉构成比为3.01%。SA直径>1 cm者占21.63%,明显大于增生性息肉(8.57%);SA表现为有蒂息肉所占的比例(8.33%)略高于增生性息肉(5.71%),但都低于腺瘤性息肉(40.84%)。SA癌变率介于管状腺瘤和绒毛状腺瘤之间,接近于管状绒毛状腺瘤。结论SA内镜形态、病理学特点提示SA是兼有增生性息肉形态学特征和腺瘤性息肉组织学特点的息肉,具有恶变潜能。
Objective To investigate the endoscopic appearance and pathological features of serrated adenoma (SA). Methods The retrospective analysis of cases of colorectal polyps detected at the Affiliated Hospital of Binzhou Medical College from January 2000 to May 2008 revealed the detection rate, endoscopic morphology and pathological features of SA. Results A total of 1 062 colorectal polyps (1 457) were detected in 8 726 colonoscopy. The detection rate was 12.17%, of which 32 were SA (60), the detection rate was 0.37%, and the polyp ratio was 3.01. %. SA diameter>1 cm accounted for 21.63%, significantly larger than hyperplastic polyps (8.57%); SA showed pedunculated polyps (8.33%) was slightly higher than hyperplastic polyps (5.71%), but both were lower than glands Tumorous polyps (40.84%). The cancerous rate of SA is between tubular adenomas and villous adenomas and is close to tubular villous adenomas. Conclusion The endoscopic morphology and pathological features of SA suggest that SA is a polyp that has both the morphological features of hyperplastic polyps and the histological features of adenomatous polyps, and has malignant potential.