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对手术根治的110例子宫内膜癌进行了临床病理分析,并对术后生存5年以上的56例进行了预后因素的探讨。110例平均发病年龄为59.8岁,平均绝经年龄为50.2岁,月经紊乱(23.6%)、不孕(28.2%)、肥胖。高血压-糖尿病(34.6%)及并发卵巢多个滤泡囊肿(32.7%)的发生率较高,表明长期持续的、缺乏孕酮对抗的雌激素刺激与发病相关。随访56例,5年生存率为83.9%,其中临床Ⅰ、Ⅱ期5年生存率为100%,Ⅲ期为42.9%,Ⅳ期为0,提示癌组织局限在子宫内时预后佳,扩散至子宫外者预后差。
A total of 110 cases of endometrial cancer undergoing radical operation were analyzed clinically and pathologically and prognostic factors were evaluated in 56 cases with postoperative survival of more than 5 years. The average age of onset was 59.8 years in 110 cases, with an average of 50.2 years of menopause, 23.6% of menstrual disorders, 28.2% of infertile women and obesity. Hypertension-diabetes mellitus (34.6%) and multiple follicular cysts in the ovaries (32.7%) reported a higher incidence of estrogen-stimulating and progesterone-resistant estrogen-stimulating events that were persistent over time. The follow-up of 56 cases showed a 5-year survival rate of 83.9%. The 5-year survival rates of stage Ⅰ and Ⅱ clinical trials were 100%, stage Ⅲ was 42.9% and stage Ⅳ was 0, which suggested that the localization of cancer in utero Good, spread to the extrauterine poor prognosis.