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先天性非溶血性黄疸又称体质性黄疸,临床少见,甚易误诊。现将我院近10年来住院确诊22例,分析报道如下: 1 临床资料 22例中,男13例,女9例。年龄16～43岁,平均年龄23.86±6.18岁。首次出现黄疸年龄1～43岁。平均16.00±9.55岁。病程4天～25年。诱因:病程中有明确原因致黄疸加重者10例(劳累7例,妊娠1例,感染1例,精神紧张1例),诱因不明12例。家族史:阳性家族史10例。临床分类:Gilbert综合征11例,Dubin-Johnson综合征8例,Rotor综合征2例,Crigler-Najjar综合征Ⅱ型1例。 症状体征:黄疸22例,乏力9例,食欲减退9
Congenital non-hemolytic jaundice, also known as physical jaundice, clinical rare, easily misdiagnosed. Now in our hospital nearly 10 years, 22 cases were diagnosed in hospital, the analysis reported as follows: 1 Clinical data 22 cases, 13 males and 9 females. Aged 16 to 43 years old, with an average age of 23.86 ± 6.18 years. Jaundice for the first time aged 1 to 43 years old. Average 16.00 ± 9.55 years old. Course of 4 days to 25 years. Incentives: There are 10 cases of jaundice exacerbated due to a specific cause in the course of the disease (7 cases of fatigue, 1 case of pregnancy, 1 case of infection, 1 case of mental stress) and 12 cases of unknown cause. Family history: Positive family history in 10 cases. Clinical classification: Gilbert syndrome in 11 cases, Dubin-Johnson syndrome in 8 cases, Rotor syndrome in 2 cases, Crigler-Najjar syndrome in 1 case. Symptoms and signs: jaundice in 22 cases, 9 cases of fatigue, loss of appetite 9