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本文对30例重度高血压病人进行了口服可乐宁的临床试验.其中男女各15人,年龄27～64岁,舒张压(DBP)>115mmHg,平均动脉压(MAP)150±2mmHg.治疗前患高血压至少1～35年,有22人伴有明显的视网膜病变Ⅱ级,12人心电图显左心室肥厚和ST波改变,5人伴有心肌梗塞病史,其中22人曾经抗高血压治疗.治疗前对病人做全面检查,包括血浆电解质含量,血、尿常规,X光胸透和心电图检查.治疗采用急性短程和慢性维持两个阶段.急性短程治疗阶段:采用的方法是短程连续给药,可乐宁首次剂量为0.1～0.2mg,然后每隔1h给0.1mg,一直
In this paper, 30 patients with severe hypertension were given oral Clonidine clinical trials, including 15 men and women of each age ranged from 27 to 64 years with diastolic blood pressure (DBP)> 115 mmHg and mean arterial pressure (MAP) of 150 ± 2 mmHg. Hypertension for at least 1 to 35 years, 22 patients with significant retinopathy Ⅱ, 12 patients with left ventricular hypertrophy and ST wave ECG changes, 5 were associated with a history of myocardial infarction, 22 of whom had antihypertensive treatment. Before the patient to do a comprehensive examination, including plasma electrolyte content, blood, urine, chest X-ray and electrocardiogram examination using acute short-term and chronic maintenance of two stages of acute short-term treatment phase: the method used is short-term continuous administration, The first dose of clonidine 0.1 ~ 0.2mg, and then every 1h to 0.1mg, has been