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血清载脂蛋白B(APO-B)含量增高,是在糖尿病糖代谢障碍基础上脂代谢异常的早期判断指标之一。肥胖是发生糖尿病,脂肪肝的重要因素。本文对58例糖尿病患者测定了血APO-B含量和肝脏B超显像观察,结果发现血脂尚正常时糖尿病APO-B值不仅高于正常对照组(P<0.01),而且高于冠心病组。其中32例肥胖型中有26例并脂肪肝(16例经CT证实),其APO-B水平及合并大血管、微血管病变发生率明显高于非肥胖型(P<0.01):血液粘度增高、血液流态、流速改变等程度,亦以肥胖型更严重。
Serum apolipoprotein B (APO-B) increased, is an early indicator of abnormal lipid metabolism based on diabetic glucose metabolism disorders. Obesity is an important factor in the development of diabetes and fatty liver. In this paper, 58 patients with diabetes mellitus were measured APO-B content and liver B ultrasound imaging, the results showed that blood lipid APO-B value is not only higher than the normal control group (P <0.01), but higher than the crown Heart disease group. Of the 32 obese patients, 26 had fatty liver (16 confirmed by CT), the APO-B level and the incidence of macrovascular and microvascular complications were significantly higher than those of non-obese (P <0.01): blood viscosity Increased blood flow, flow rate changes, etc., but also to more serious obesity.