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目的:评价甲硝唑片与复方克霉唑阴道栓联用对妊娠合并生殖道感染孕妇妊娠结局的影响。方法:选取2013年1月—2014年1月期间收治的妊娠合并生殖道感染孕妇98例,将其分为对照组(48例)和观察组(50例);对照组患者给予加强清洁卫生,定期随访;观察组患者在对照组基础上给予甲硝唑片与复方克霉唑阴道栓联用治疗,评价两组患者临床疗效及其对妊娠结局的影响。结果:观察组患者治疗后的治愈率明显高于对照组(P<0.05),其不良妊娠率明显低于对照组(P<0.05)和新生儿并发症的发生率明显低于对照组(P<0.05)。结论:甲硝唑片与复方克霉唑阴道栓联用有助于改善妊娠合并生殖道感染患者妊娠结局。
Objective: To evaluate the effect of metronidazole tablets combined with clotrimazole vaginal suppository on pregnancy outcomes in pregnant women with genital tract infection. Methods: A total of 98 pregnant women with genital tract infection during pregnancy from January 2013 to January 2014 were selected and divided into control group (48 cases) and observation group (50 cases). Patients in the control group were enrolled in the study to enhance hygiene, The patients in the observation group were given metronidazole tablets combined with clotrimazole vaginal suppository on the basis of the control group, and the clinical efficacy and the effect on the pregnancy outcome in the two groups were evaluated. Results: The cure rate of observation group was significantly higher than that of control group (P <0.05), and the rate of adverse pregnancy was significantly lower than that of control group (P <0.05) and neonatal complication rate was significantly lower than that of control group (P <0.05). Conclusion: The combination of metronidazole tablets and clotrimazole vaginal suppository may be helpful to improve pregnancy outcome in pregnancy complicated with genital tract infection.