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返流性肾病(Reflux Nephroparhy)是膀胱输尿管返流(VUR)导致肾盂肾炎、局灶性及广泛性的肾瘢痕、慢性肾萎缩,最后出现肾衰竭的一种慢性疾病.因其临床表现复杂多样,曾有各种命名:慢性肾盂肾炎、先天性节段性(肾)发育不良、ASK-UPmark 肾、原发性间质肾炎。1973年 Bailet 提出返流性肾病名称,五年后英国 Lancet 编者明确提出该病与膀胱输尿管返流、肾小管逆流(IRR),和尿路感染(UTI)密切相关。
Reflux Nephroparhy is a chronic disease of vesicoureteral reflux (VUR) leading to pyelonephritis, focal and extensive renal scarring, chronic renal atrophy, and finally to renal failure, because of its complex and diverse clinical manifestations , There have been various names: chronic pyelonephritis, congenital segmental (renal) dysplasia, ASK-UPmark kidney, primary interstitial nephritis. In 1973, Bailet proposed the name of reflux nephropathy. Five years later, the editor of Lancet in England made it clear that the disease is closely related to vesicoureteral reflux, renal tubular reflux (IRR), and urinary tract infection (UTI).