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目的分析获得性免疫缺陷综合征(AIDS)患者经过高效抗逆转录病毒治疗(HAART)后发生免疫重建炎性综合征(IRIS)肺结核感染的胸部CT表现特点。方法回顾性分析30例经高效抗逆转录病毒治疗后发生IRIS的AIDS患者的胸部CT图像及临床资料探讨其特征性表现。结果 30例患者中肺内出现弥漫性病变伴结节影20例,出现肺内结节影、条片影17例,粟粒性肺结核15例,纵隔、肺门淋巴结肿大10例,胸腔积液15例,心包积液10例。结论两肺弥漫病变伴粟粒样结节影是AIDS发生IRIS结核病感染最显著的胸部CT影像表现特点,可伴或不伴淋巴结肿大或胸腔积液或心包积液。
Objective To analyze the chest CT findings of patients with Acquired Immune Deficiency Syndrome (AIDS) who have undergone infection with immunosuppressed inflammatory syndrome (IRIS) after highly active antiretroviral therapy (HAART). Methods A retrospective analysis of thoracic CT images and clinical data of 30 AIDS patients who developed IRIS after intensive antiretroviral therapy was performed to investigate their characteristic manifestations. Results Thirty patients had diffuse lesions with nodules in the lungs, 20 cases of pulmonary nodules, slides in 17 cases, miliary tuberculosis in 15 cases, mediastinal, hilar lymphadenopathy in 10 cases, pleural effusion 15 cases, 10 cases of pericardial effusion. Conclusions The diffuse lesions of both lungs with miliary nodules are the most prominent manifestations of chest CT in AIDS-infected patients with IRIS, with or without enlarged lymph nodes or pleural effusion or pericardial effusion.