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１９８８～１９８９ 年在东非索马里南部对恶性疟现症患者用复方苯芴醇治疗２６ 例和氯喹治疗 １４ 例，以退热时间、原虫无性体转阴时间和随访２８ ｄ 治愈率等指标评价疗效。结果表明，复方苯芴醇和氯喹相比，退热时间相当，而原虫无性体转阴时间和随访２８ ｄ 治愈率，前者明显优于后者。前者治疗３ 例抗氯喹恶性疟患者均治愈。无免疫力患者的退热时间较有免疫力者慢，但原虫转阴时间和随访 ２８ ｄ 治愈率，两者相当；对配子体的杀灭效果不甚理想。本研究结果为复方苯芴醇在非洲恶性疟流行地区的临床应用提供了参考资料。
From 1988 to 1989, 26 cases were treated with compound lutrenol and 14 cases were treated with chloroquine in the southern Somalia, eastern part of the country. The curative effect was evaluated by the time of fever relief, the time of asexual protozoan aversion and the follow-up of 28 days. The results showed that the combination of meflulone and chloroquine, antipyretic time is quite, while protozoa asexual negative time and follow-up 28d cure rate, the former was significantly better than the latter. The former treatment of 3 cases of anti-chloroquine falciparum malaria were cured. Antiimmunity patients with antipyretic time is slower than those with immunity, but protozoa negative time and follow-up 28d cure rate, the two are quite; the gametophyte killing effect is less than ideal. The results of this study provide a reference for the clinical application of compound lumefantrine in the endemic area of P. falciparum in Africa.