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目的:介绍固体脂质纳米粒的制备方法、应用。方法:参阅国内外文献,进行分析,归纳和总结。结果:固体脂质纳米粒是一种新型药物传递载体,具有靶向、控释、提高药物稳定性、毒性小、可大批量生产等优点。现综述了近年来国内外固体脂质纳米粒的制备方法和应用。结论:固体脂质纳米粒虽还有一些问题有待解决,但却是一个很有发展潜力的给药系统。
Objective: To introduce the preparation and application of solid lipid nanoparticles. Methods: Refer to the literature at home and abroad, analyze, summarize and summarize. Results: The solid lipid nanoparticles are a new type of drug delivery carrier with advantages of targeting, controlled release, drug stability, low toxicity and mass production. Now reviewed the preparation methods and applications of solid lipid nanoparticles at home and abroad in recent years. Conclusion: Although there are still some problems to be solved for solid lipid nanoparticles, it is a promising drug delivery system.