论文部分内容阅读
目的观察不同剂量阿托伐他汀钙治疗不稳定型心绞痛的临床效果。方法选取医院收治的不稳定型心绞痛患者88例,根据用药剂量不同分为甲组(44例,20mg/d)、乙组(44例,60mg/d),观察比较2组患者的临床疗效、心绞痛发作次数及不良心血管事件发生情况。结果甲组患者治疗总有效率为79.5%,心绞痛发作次数为(7.7±0.8)次/周,不良心血管事件发生率为29.5%;与乙组的95.5%、(3.1±0.3)次/周、11.4%比较,差异均有统计学意义(P<0.05)。结论在不稳定型心绞痛治疗中,大剂量阿托伐他汀的治疗效果显著优于常规剂量,可有效减少心绞痛发作次数与不良心血管事件的发生率,值得临床推广应用。
Objective To observe the clinical effects of different doses of atorvastatin calcium in the treatment of unstable angina pectoris. Methods Eighty-eight patients with unstable angina pectoris admitted to hospital were divided into group A (44 cases, 20 mg / d) and group B (44 cases, 60 mg / d) according to the dosage. The clinical efficacy, Angina pectoris episodes and adverse cardiovascular events. Results The total effective rate of treatment in group A was 79.5%, the incidence of angina pectoris was 7.7 ± 0.8 / week and the incidence of adverse cardiovascular events was 29.5%. Compared with 95.5% in group B (3.1 ± 0.3) / week , 11.4%, the differences were statistically significant (P <0.05). Conclusions In the treatment of unstable angina, high-dose atorvastatin treatment is significantly better than the conventional dose, which can effectively reduce the incidence of angina pectoris episodes and adverse cardiovascular events, worthy of clinical application.