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目的观察奥美拉唑、阿莫西林、甲硝唑三联疗法对消化性溃疡的疗效。方法把近2年来在我科门诊治疗的十二指肠溃疡患者200例随机分为治疗组和对照组,治疗组100例,采用奥美拉唑、阿莫西林、甲硝唑组成的三联疗法治疗;对照组100例,采用雷尼替丁、呋喃唑酮、甲硝唑组成的三联疗法治疗。2组患者均于4周后复查胃镜,用有效率作为评定疗效的指标。结果由奥美拉唑、阿莫西林、甲硝唑组成的三联疗法治疗十二指肠溃疡有效率显著高于由雷尼替丁、呋喃唑酮、甲硝唑组成的三联疗法。结论三联药物奥美拉唑、阿莫西林、甲硝唑治疗消化性溃疡疗效好,不良反应少。
Objective To observe the curative effect of omeprazole, amoxicillin and metronidazole triple therapy on peptic ulcer. Methods A total of 200 patients with duodenal ulcer treated in our department during the past 2 years were randomly divided into treatment group and control group. The treatment group consisted of 100 patients with triple therapy of omeprazole, amoxicillin and metronidazole Treatment; control group of 100 cases, the use of ranitidine, furazolidone, metronidazole triple therapy. The patients in both groups were examined for endoscopy after 4 weeks, and the effective rate was used as an index to evaluate the curative effect. Results The triple therapy of omeprazole, amoxicillin and metronidazole was superior to triple therapy in the treatment of duodenal ulcer with ranitidine, furazolidone and metronidazole. Conclusion The triple drug omeprazole, amoxicillin, metronidazole in the treatment of peptic ulcer with good efficacy and few adverse reactions.