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目的：探讨柯萨奇Ｂ组病毒（ＣＶＢ）引起的神经系统病变的临床特征。方法：采用酶联免疫吸附试验，用ＣＶ１～６Ｂ型抗原分别测定２４例患者血清中ＩｇＭ、ＩｇＧ抗体。结果：２４例患者中由ＣＶＢ感染者１１例，占４５．８％，其中脑膜炎５例，脑炎３例，痛性眼肌麻痹、病毒性肌无力、单纯性头痛各１例。９例为近期感染，２例为远期感染。结论：由于ＣＶＢ毒株型不同，故临床表现复杂多样，临床上应予重视。
Objective: To investigate the clinical characteristics of Coxsackie B virus (CVB) -induced neurological diseases. Methods: Serum IgM and IgG antibodies of 24 patients were tested by enzyme-linked immunosorbent assay (ELISA) and CV1-6B antigen respectively. Results: Among the 24 patients, 11 cases were infected by CVB, accounting for 45.8%, including 5 cases of meningitis, 3 cases of encephalitis, 1 case of painful ophthalmoplegia, viral myasthenia and simple headache. Nine cases were recent infections and two cases were long-term infections. Conclusion: Due to the different strains of CVB strains, the clinical manifestations are complex and diverse and should be taken seriously in clinical practice.