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目的:观察舒血宁注射液与低分子肝素联合治疗不稳定型心绞痛的临床疗效。方法:将80例患者随机分为治疗组和观察组各40例,两组均给予硝酸酯类、β受体阻滞剂、钙拮抗剂、小剂量阿司匹林、他汀类药,治疗组加用中药舒血宁注射液20 m l加入5%葡萄糖注射液或生理盐水250 m l静脉滴注,疗程14 d;同时加用低分子肝素5 000 U腹壁皮下注射,每12 h 1次,连用7 d为1个疗程。结果:心绞痛症状缓解总有效率治疗组为95%,西药组为75%(P<0.05);心电图总有效率分别为80%及55%(P<0.05)。结论:舒血宁注射液与低分子肝素联合治疗不稳定型心绞痛能有效缓解心绞痛症状,减少心绞痛发作次数,缩短发作时间,同时心电图也有明显改善,综合疗效显著优于观察组。
Objective: To observe the clinical effect of Shuxuening injection combined with low molecular weight heparin in the treatment of unstable angina pectoris. Methods: Eighty patients were randomly divided into treatment group and observation group, with 40 cases in each group. Nitrates, β-blockers, calcium antagonists, low-dose aspirin, statins, Shuxuening injection 20 ml added 5% glucose injection or saline 250 ml intravenous infusion, treatment 14 d; plus low molecular weight heparin 5 000 U abdominal subcutaneous injection, once every 12 h, once every 7 d 1 A course of treatment. Results: The total effective rate of angina pectoris was 95% in the treatment group and 75% in the western medicine group (P <0.05). The total effective rate of ECG was 80% and 55% respectively (P <0.05). Conclusion: Shuxuening injection and low molecular weight heparin combined treatment of unstable angina pectoris can effectively relieve angina pectoris, reduce the number of angina pectoris and shorten the attack time, ECG also significantly improved, the comprehensive effect was significantly better than the observation group.