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利尿药常用于治疗水肿。但是,人们对给利尿药后体液中浓度却很少注意。使用洋地黄、抗癫痫药时监测血中浓度几乎已成为常规。而利尿药,例如速尿给予过多可增强肾毒性物质的毒性,所以医师必须力图用最小剂量取得最大效果。今后要测定各种利尿药在体液中的浓度,监测其体内药物动力学状态,做到合理用药。作者结合自己的实践经验,对常用治疗水肿药物:(1)噻嗪类药物(双氢克尿噻),(2)
Diuretics are commonly used to treat edema. However, little attention has been given to the concentration of diuretics in body fluids. Using digitalis, antiepileptic drugs to monitor blood concentration has almost become routine. And diuretics, such as furosemide to give too much can increase the toxicity of nephrotoxic substances, so physicians must try to get the maximum effect with the minimum dose. In the future to determine the concentration of diuretics in body fluids, monitoring the body’s pharmacokinetic status, so that rational use of drugs. The author combined his own practical experience, the commonly used treatment of edema drugs: (1) thiazide drugs (hydrochlorothiazide), (2)