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本文报道了氨噻羧单胺菌素和其他β-内酰胺类抗生素间的低交叉过敏反应性以及对人的弱免疫原性.尽管青霉素和头孢菌素的侧链组成有显著不同,但由于它们具有相似的母核结构,因此在免疫学上已被证明它们之间能发生不同程度的交叉过敏反应.氨噻羧单胺菌素(SQ26776)是一个新开发的全合成的单环β-内酰胺类抗生素,对需氧革蓝氏阴性菌有强大的杀菌作用并已成功地用于治疗,是一个很有发展前途的抗生素.本文用免疫学的方
This article reports the low cross-allergic reactivity between amiloxins and other beta-lactam antibiotics and their weak immunogenicity to humans Although there are significant differences in the side-chain composition of penicillins and cephalosporins, They have a similar nuclear structure and therefore immunologically have been shown to occur between them to varying degrees of cross-allergic reactions.Athiocarbamicin (SQ26776) is a newly developed fully synthetic monocyclic β- Lactam antibiotics, has a strong bactericidal effect on aerobic gram-negative bacteria and has been successfully used for treatment, is a very promising antibiotics.In this paper,