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1978～1992年收治原发性肾病综合征70例,男55例,女15例;年龄15个月～13岁半。临床分型:单纯型59例,肾炎型11例。初治52例,再治18例。强的松用量按1.5～2.0mg/kg·d。治疗2周尿蛋白转阴后续用8周,尿蛋白持续阴性为激素敏感共50例(71.4％);尿蛋白有减少,但仍在(++)～(+)为部分敏感,共4例(5.7％);虽浮肿减轻尿蛋白始终在(+++)以上为不敏感共16例(22.9％)。不敏感组中肾炎型占9例,单纯型占7例。单纯型加用CTX4例,加用CB3例,待尿蛋白转阴后,强的松改为2mg/kg·d隔日治疗,逐渐减
From 1978 to 1992, 70 cases of primary nephrotic syndrome were admitted, including 55 males and 15 females; their ages ranged from 15 months to 13 years and a half. Clinical classification: simple type in 59 cases, nephritis in 11 cases. The initial treatment of 52 cases, re-treatment of 18 cases. Prednisone dosage by 1.5 ~ 2.0mg / kg · d. After 2 weeks of treatment, urinary protein was negative for 8 weeks, urinary protein was negative for hormone sensitivity in 50 cases (71.4%), urinary protein was decreased, but (++) ~ (+) was still partly sensitive, a total of 4 cases (5.7%). Although edema alleviates urine protein, it is always insensitive to (+++) in 16 cases (22.9%). Nephritis in the non-sensitive group accounted for 9 cases, simple type accounted for 7 cases. Simplex plus CTX4 cases, plus CB3 cases, to be negative urine protein, prednisone changed 2mg / kg · d every other day, and gradually reduced