论文部分内容阅读
本实验采用ＤＭＢＡ（二甲基苯丙蒽）丙酮局部涂抹法成功地建立了金地鼠颊囊癌前病变的动物模型。与此同时应用复方绞股蓝进行了对口腔粘膜癌前病变阻断的实验研究。结果显示：绞股蓝对口腔粘膜癌前病变的阻断部位发生在均质型白斑到颗粒状白斑或疣状白斑阶段。先服绞股蓝后涂ＤＭＢＡ组优于边涂边服组。实验证明绞股蓝具有防癌和抗癌功能，在口腔粘膜癌前病变的防治中具有应用前景，其抗癌机理还有待于作更深入的研究。
In this experiment, DMBA (dimethyl benzophenanthracene) acetone topical smear method successfully established the golden hamster cheek pouch precancerous lesions in animal models. At the same time, compound gypenosides was used to block the precancerous lesions of oral mucosa. The results showed that Gynostemma occured in the stage of homogenous leukoplakia to leukoplakia or verrucous leukoplakia on the precancerous lesion of oral mucosa. After the first service Gynostemma DMBA coated group was better than the edge coated service group. Experiments show that Gynostemma has anti-cancer and anti-cancer function in the prevention and treatment of oral mucosal precancerous lesions with application prospects, the anticancer mechanism remains to be further studied.