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Objective: To evaluate the therapeutic effect of Juanxiao Tablet (JXT) in treating asthma. Methods: Clinical observation on 447 cases of asthma was done in double or single blinded control method, and the therapeutic effect and safety of JXT were analysed. The effect of JXT in anti asthma, expectorant, antisepsis, hypoxia tolerance was studied, and its acute and chronic toxicity was also examined. Results: The clinical control rate in patients treated with JXT was 38.2%, the markedly effective rate 31.2% and the total effective rate 93.4%, whereas in patients treated with Oleum Vitex Negundo, the respective rates were 13.3%, 20.0% and 68.5%. Results of pulmonary function and IgE measurement were consistent with clinical effect. Experimental study showed that JXT has the actions of anti asthma, expectorant, antisepsis and hypoxia tolerance enhancement, with its LD 50 (40.48±5.17) g/kg.Conclusion: JXT is a new Chinese herbal preparation of good effect, with less toxic side effect for asthma treatment.
Objective: To evaluate the therapeutic effect of Juanxiao Tablet (JXT) in treating asthma. Methods: Clinical observation on 447 cases of asthma was done in double or single blinded control method, and the therapeutic effect and safety of JXT were analyzed. The effect of JXT in anti asthma, expectorant, antisepsis, hypoxia tolerance was studied, and its acute and chronic toxicity was also examined. Results: The clinical control rate in patients treated with JXT was 38.2%, the markedly effective rate 31.2% and the total effective rate 93.4%, while in patients treated with Oleum Vitex Negundo, the respective rates were 13.3%, 20.0% and 68.5%. Results of pulmonary function and IgE measurements were consistent with clinical effect. Experimental study showed that JXT has the actions of anti asthma, expectorant, antisepsis and hypoxia tolerance enhancement, with its LD 50 (40.48 ± 5.17) g / kg. Conclusion: JXT is a new Chinese herbal preparation of good effect, with less toxic side e ffect for asthma treatment.