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目的 :开发新型表面修饰人工晶状体 ,以减少后囊混浊。方法 :13只猕猴分 3组 ,分别植入 PMMA IOL、 Pharmacia HSMIOL、氟 -肝素表面修饰 IOL。于术后 15、 30、 6 0、 90、 180天裂隙灯检查后囊混浊形成情况。术后 180天摘除眼球 ,光镜检查。结果 :后囊混浊于术后 30天形成 ,90天明显。术后 90、 180天实验组引起后囊混浊程度最轻。后囊混浊的病理变化有纤维内障、Elschnig小体、 Soemmerring s环。结论 :氟 -肝素表面修饰人工晶状体植入猕猴眼引起后囊混浊的程度轻 ,生物相容性好
Objective: To develop a new type of surface-modified intraocular lens to reduce posterior capsular opacity. Methods: Thirteen macaque monkeys were divided into three groups and were respectively implanted with PMMA IOL, Pharmacia HSMIOL and fluoro-heparin surface modification IOL. After 15, 30, 60, 90, 180 days slit lamp examination posterior capsule opacification. 180 days after removal of the eye, light microscopy. Results: Posterior capsular opacification was formed 30 days after operation and was obvious on the 90th day. After 90, 180 days the experimental group caused the lightest posterior capsule opacity. Posterior capsule opacity pathological changes are cataract, Elschnig body, Soemmerring s ring. Conclusion: Fluoro-heparin surface-modified intraocular lens implanted in the eyes of the monkey posterior posterior capsular opacification degree of light, good biocompatibility