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报告1983年5—7月银川市托幼机构6个月以上、7周岁以下儿童口服二个月铁剂(相当于元素铁4mg/kg/日)后的一年远期防治效果。治疗组56名,同机构同龄对照组26名(两组婴幼儿分别有54.6％和57.7％患铁缺乏症)。治疗组治前血红蛋白(Hb)和红细胞内游离原卟啉/血红蛋白比值(FEP/Hb)之(?)±SD及血清铁蛋白(SF)之(?)G分别为11.4±1.09g/dl,3.359±1.229μg/g及14.0(1.4—118)ng/ml;治疗后分别转成12.4±0.9g/dl,2.282±0.645μg/g及41.3(14.4—268)ng/ml。治疗前、后Hb、FEP/Hb及SF三对均值间各各的差异均显著(t分别为5.562,5.807,6.240,P均<0.001),说明短期口服铁剂确可改善学龄前儿童的缺铁状态。次年5月,治疗组(Hb12.3±1.2g/dl,FEP/Hb2.744±1.679μg/g)与对照组(Hb11.6±0.9g/dl,FEP/Hb3.716±2.378μg/g)两对均值间各各的铁状态差异虽均显著(P均<0.05);但治疗组与对照组铁缺乏症患病率(30.4％和46.2％)之间却并无显著差异(T=1.368,P>0.05),提示短期口服铁剂虽对铁缺乏症有一定的预防作用,可是,为了保证持续效果,尚应采取期间更长些的药物和强化食品的防治措施。
The one-year long-term prevention and control effect of oral iron for two months (equivalent to 4 mg / kg / day of elemental iron) of children aged 7 months and younger from Yinchuan City in 5-July 1983 was reported. 56 in the treatment group and 26 in the control group with the same age (54.6% and 57.7% of the children with and without iron deficiency respectively). The values of ± SD and F G of Fp / Hb and Hb in the treatment group were 11.4 ± 1.09g / dl, 3.359 ± 1.229μg / g and 14.0 (1.4-118) ng / ml respectively; after treatment, they were converted to 12.4 ± 0.9g / dl, 2.282 ± 0.645μg / g and 41.3 (14.4-268) ng / ml respectively. The mean of three pairs of Hb, FEP / Hb and SF before and after treatment were all significantly different (t = 5.562,5.807,6.240, P <0.001, respectively), indicating that short-term oral iron can improve the lack of preschool children Iron status. In the following May, the treatment group (Hb12.3 ± 1.2g / dl, FEP / Hb2.744 ± 1.679μg / g) and the control group (Hb11.6 ± 0.9g / dl, FEP / Hb3.716 ± 2.378μg / g) There was no significant difference in iron status between the two pairs of means (P <0.05), but there was no significant difference between the treatment group and the control group (30.4% vs 46.2%) (T = 1.368, P> 0.05), suggesting that although short-term oral iron has a certain preventive effect on iron deficiency, in order to ensure sustained effect, we should take longer period of drug and food control measures.