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肿瘤细胞多药耐药的机制与ｍｄｒ１（ｍｕｌｔｉｄｒｕｇｒｅｓｉｓｔａｎｃｅｇｅｎｅ）基因的过度表达有关．该基因产物是Ｍｒ１７００００Ｐ糖蛋白（Ｐｇｐ）．Ｐ糖蛋白有药物联接特性，还可以作为一种依赖能量的药物输出泵．在结肠癌治疗过程中常发现患者对某药或某
The mechanism of multidrug resistance in tumor cells is related to the overexpression of mdr1 (multidrugresistancegene) genes. The gene product is Mr170000P glycoprotein (P gp). P glycoprotein has drug connection characteristics, can also be used as an energy-dependent drug output pump. During the treatment of colon cancer, it is often found that the patient