论文部分内容阅读
目的:研究呼吸机相关性肺炎鲍氏不动杆菌感染的临床特征。方法:选取2010年1月到2015年1月我院收治的应用呼吸机患者130例,根据是否合并肺炎鲍氏不动杆菌感染将患者分为研究组(86例)和对照组(44例),分析呼吸机相关性肺炎鲍氏不动杆菌的临床特征,然后根据药敏实验选择应用药物进行治疗,并观察治疗效果。结果:呼吸机相关性肺炎鲍氏不动杆菌感染的分布科室主要以ICU为主,大约为76.74%,神经外科次之,大约为8.14%;研究组呼吸机应用时间(18.72±3.15)天显著长于对照组(6.18±0.02)天,两组比较差异具有统计学意义(P<0.05);研究组经舒巴坦联合左氧氟沙星或者亚胺培南治疗后总有效率为91.86%。结论:呼吸机相关性肺炎鲍氏不动杆菌多发生于ICU,且感染者呼吸机应用时间较长,联合治疗效果显著。
Objective: To study the clinical features of Acinetobacter baumannii infection in ventilator-associated pneumonia. Methods: A total of 130 patients with ventilator admitted to our hospital from January 2010 to January 2015 were divided into study group (86 cases) and control group (44 cases) according to whether they had Acinetobacter baumannii infection. , Analyze the clinical features of Acinetobacter baumannii in ventilator-associated pneumonia, and then select the drugs according to the susceptibility test for treatment, and observe the therapeutic effect. Results: The main distribution of Acinetobacter baumannii in ventilator-associated pneumonia was ICU, accounting for about 76.74%, followed by neurosurgery for about 8.14%. The ventilator application time in study group was (18.72 ± 3.15) days significantly (6.18 ± 0.02) days, the difference between the two groups was statistically significant (P <0.05). The total effective rate of the study group after treatment with sulbactam plus levofloxacin or imipenem was 91.86%. CONCLUSION: Acinetobacter baumannii in ventilator-associated pneumonia mostly occurs in the ICU, and the ventilator in infected patients is used for a long time, and the combination therapy has a significant effect.