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多年来许多学者以实验和临床观察证明,动脉粥样硬化和冠心病的发生与血液凝固性的改变有密切联系。自Needleman(1975)Moncada(1976)发现血小板和血管壁前列腺素代谢在动脉粥样硬化和心肌梗塞发生中起重要作用后,近年来对血小板功能改变在动脉粥样硬化发生中的作用更为重
Over the years many scholars with experimental and clinical evidence that atherosclerosis and coronary heart disease and blood clotting changes are closely linked. In recent years, the role of platelet function changes in the development of atherosclerosis has been more pronounced in recent years since Needleman (1975) Moncada (1976) found that platelet and vascular wall prostaglandin metabolism plays an important role in the development of atherosclerosis and myocardial infarction