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目的对医学期刊治疗性研究文献质量进行评价。方法手工翻阅《医学研究生学报》近10年的文献,筛选出其中的临床治疗性研究,对RCT的文献(排除有对照非随机及未设对照的叙述性研究)进行标注同时进行质量评估。结果 2000-2010年《医学研究生学报》共刊载文献3 644篇,临床治疗性文献1 433(39.76%,1 312/3 300)篇,包括随机对照试验研究、回顾性病例总结、断面调查及病例报告等,其中随机对照试验(RCT)研究99篇。在RCT文献中,仅有12篇文献描述了随机方法,17篇文献描述了盲法,60篇文献对治疗组及对照组的一般情况都进行了对比并给出了统计学分析,有72篇文献描述了副作用。结论 RCT试验报告质量仍然需要进一步的提高。
Objective To evaluate the quality of medical research literature in medical journals. Methods Manually read through the medical journals for nearly 10 years, screened out the clinical therapeutic research, and evaluated the quality of the RCT literature (excluding non-randomized and non-controlled narrative studies). Results A total of 3 644 articles were published in the Journal of Medical Graduates from 2000 to 2010, and 1 433 (39.76%, 1 312/3 300) articles were included in the literature, including randomized controlled trials, retrospective case reports, cross-sectional surveys and cases Reports, etc., of which 99 randomized controlled trials (RCT) study. In the RCT literature, only 12 articles described the randomized method, 17 articles described the blind method, 60 articles compared the general situation of the treatment group and the control group with statistical analysis and 72 articles The literature describes side effects. Conclusion The quality of RCT test report still needs to be further improved.