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目的：评价青少年安氏Ⅱ类2分类错牙合患者正畸治疗前后颅颌面结构的变化。方法：测量分析12例青少年安氏Ⅱ类2分类错牙合患者正畸治疗前后的头颅定位侧位X线片上的各项指标。结果：正畸治疗后，前颅底长增加，上颌骨矢状向长度无明显变化，下颌骨体部、升支及下颌骨总长度增加，上、下、前、后面高增大；腭平面、下颌平面无明显旋转，前后面高比值无显著变化；SNA减小，SNB无显著变化，ANB角减小，Y轴角增大。SNB在治疗前后的差值与下颌骨总长、体部、升支治疗前后差值呈显著正相关，ANB在治疗前后的差值与下颌骨总长及升支治疗前后差值呈显著负相关。结论：正畸治疗可以改善青少年患者颅颌面结构缺陷。下颌骨垂直向以及水平向的生长有助于上下颌骨Ⅱ类关系的改善。“,”Objective:To assess the changes of craniomaxillofacial morphology in adolescents with Angle Class II Division 2 malocclusion after orthodontic treatment .Methods:The indexes of lateral cephalometric radiographs of 12 adolescents with Angle ClassⅡ Division 2 malocclusion before and after orthodontic treatment were measured and analyzed .Results:After orthodontic treatment , length of anterior skull base(SN) increased .There was no significant change in maxillary sagittal length .Go‐Gn ,Cond‐Go ,and total length of mandible(Co‐Gn) increased .S‐Go ,N‐Me ,lower facial height ,and upper facial height ,increased .Palatal plane(ANS‐PNS) and mandibular plane(MP) did not rotate significantly .There was no significant change in S‐Go/N‐Me ration .SNA decreased .No significant change happened to SNB .ANB decreased .Y axis angle increased .A significant positive correlation was found between the changes of SNB and those of mandibular length ,Go‐Gn ,and Gond‐Go .There is also a significant inverse correlation between the changes of ANB and those of Cond‐Go and Mandibular length .Conclusions:The orthodontic treatment can effectively improve craniomaxillofacial morphology defects in adolescents with Class II Division 2 malocclusion .The vertical and horizontal direction growth of mandible is conducive to the correction of Angl Class II malocclusion .