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抗菌药物滥用可导致细菌耐药性增长、药源性疾病增多、患者住院时间及费用增加、社会医药资源浪费等一系列问题。合理使用抗菌药物是医院管理的重点和难点。临床中普遍存在微生物学送检率较低、抗菌药物使用比例过高、药物选择不合理、围手术期预防用药不规范及联合用药无指征等问题。加强病原学检验、完善抗菌药物临床应用技术支撑体系、积极开展抗菌药物合理使用继续教育与培训等是促进抗菌药物合理使用的有效手段。
Antibacterial drug abuse can lead to increased bacterial resistance, drug-induced diseases, increased hospitalization time and costs, social waste of resources and a series of issues. Rational use of antimicrobial agents is the focus of hospital management and difficulties. Clinical prevalence of microbiological delivery rate is low, the use of anti-bacterial drugs is too high, the choice of drugs unreasonable, non-standard perioperative prophylaxis and medication without indications and other issues. To strengthen the etiological test, improve the clinical application of antibacterial drugs technology support system, and actively carry out the rational use of antimicrobial agents continue education and training is to promote the rational use of antimicrobial agents an effective means.