论文部分内容阅读
目的:评价鼻咽癌1992分期和2008分期对远处转移的预测价值,为鼻咽癌分期系统的进一步修订和完善提供建议。方法:收集2004-01-01-2004-12-31中山大学肿瘤医院初治经病理学确诊无远处转移且有鼻咽和颈部MRI资料的鼻咽癌住院患者781例,比较两种分期系统各T、N及临床分期与转移的关系。结果:在T分期方面,2008分期对远处转移的预测价值优于1992分期;在N分期方面,2008和1992分期各有优势。2008分期N1a远处转移风险比(HR)及死亡风险比与N0较接近,将这部分患者归为T分期后,各N分期对远处转移的预测更合理。结论:2008分期系统在预测远处转移方面优于1992分期系统。颈部淋巴结阴性患者的咽后淋巴结归属问题值得进一步探讨。
OBJECTIVE: To evaluate the predictive value of nasopharyngeal carcinoma (NPC) in 1992 staging and 2008 staging for distant metastasis, and to provide suggestions for further revision and improvement of staging system of NPC. METHODS: A total of 781 NPC patients with nasopharyngeal carcinoma who had no history of distant metastasis and had nasopharyngeal and cervical MRI data from 2004-01-01-2004-12-31 were recruited from Cancer Center of Sun Yat-sen University. System of T, N and clinical stage and the relationship between metastasis. Results: In terms of T staging, the predictive value of 2008 staging for distant metastasis was better than that of 1992 staging. For staging N, 2008 and 1992 staging had their own advantages. 2008 staging N1a distant metastasis risk ratio (HR) and risk of death close to the N0, this part of the patients classified as T stage, the N stage prediction of distant metastasis more reasonable. Conclusions: The 2008 staging system is superior to the 1992 staging system in predicting distant metastases. Neck lymph node-negative patients with posterior pharyngeal lymph node attribution problems worth further study.