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目的：观察抗感宁胶囊的抗炎作用及急性毒性。方法：以大鼠蛋清、角叉菜胶足跖注射致炎法和分组法。结果：抗感宁灌胃给药（０ ．８ ，０．４ ，０ ．２ｇ／ｋｇ） 对二种致炎模型均有明显抗炎作用，于３０ｍｉｎ 开始起效，可维持６ｈ 之外，３ 剂量间存在量效关系。用ｂｌｉｓｓ 法算得大鼠和小鼠灌胃的ＬＤ５０分别为１０．４６ｇ／ｋｇ 和４ ．６８ｇ／ｋｇ 。结论：抗感宁具有明显抗炎作用，且毒性较小。
Objective: To observe the anti-inflammatory effects and acute toxicity of Kangganing Capsule. METHODS: Rats with egg white and carrageenan injections were injected into the inflamed and grouped methods. RESULTS: The anti-inflammation administration of gavage (0.8, 0.4, 0.2 g/kg) had obvious anti-inflammatory effects on the two kinds of inflammation models, and began to take effect at 30 minutes, which could be maintained for 6 hours. 3 There is a dose-effect relationship between doses. Using the bliss method, the LD50 of rats and mice were 10.46 g/kg and 4. respectively. 68g/kg. Conclusion: Anti-inflammation has obvious anti-inflammatory effect and less toxicity.