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本实验室随机选择被动吸烟孕妇及正常孕妇各３０例进行ＳＣＥ表达频率的研究，而且选择检测组中１５例服用叶酸试验治疗，对比值有显著差异。检测组ＳＣＥ表达频率为３．６％，对照组子代ＳＣＥ表达频率为２．８％；服用叶酸检测组ＳＣＥ表达频率为５．７％，未服用叶酸检测组ＳＣＥ表达频率为７．３％；研究数据提示被动吸烟可诱发ＳＣＥ表达频率增高，从而使染色体不稳定性增加，染色体畸变率增高。ＳＣＥ表达频率频繁的染色体及部位有２ｐ１１、３ｐ１４、９ｐ１２、１１ｐ１１、１６ｐ１１、２１ｐ１３、Ｘｐ２３。
The laboratory randomly selected passive smoking pregnant women and normal pregnant women 30 cases of SCE expression frequency of study, and select the test group of 15 patients taking folic acid test treatment, the contrast value was significantly different. The frequency of SCE expression in test group was 3.6%, that of control group was 2.8%, that of folic acid test group was 5.7%, that of non-folic acid test group was 7.3% ; Research data suggest that passive smoking can induce SCE expression increased frequency, resulting in increased chromosome instability, increased chromosome aberration rate. SCE frequent expression of chromosomes and sites have 2p11, 3p14, 9p12, 11p11, 16p11, 21p13, Xp23.