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以肾小球损害为主要病变的肾病综合征(NS)可为恶性肿瘤的全身并发症之一。并发NS的恶性肿瘤包括各种类型的上皮性癌、Hodgkin病、非Hodgkin淋巴瘤、白血病,各种胚胎性肿瘤、多发性骨髓瘤等。癌肿患者的肾小球损害以膜性肾炎为主;Hodgkin病等淋巴系统肿瘤则以微小病变型肾炎为主。前者与免疫复合物有关,后者与淋巴激活素的生成有关。恶性肿瘤常并发弥漫性血管内凝血(DIC),而
Nephrotic syndrome (NS), which is a major lesion of glomerular damage, may be one of the systemic complications of malignant tumors. Malignancies with NS include various types of epithelial cancer, Hodgkin’s disease, non-Hodgkin lymphoma, leukemia, various embryonal tumors, multiple myeloma and the like. Glomerular damage in patients with cancer mainly membranous nephritis; Hodgkin disease and other lymphatic system tumors are minimally pathological nephritis. The former is related to immune complexes, which are related to the production of lymphotactin. Malignant tumors often complicated by diffuse intravascular coagulation (DIC), and