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近年来,许多报道第三代喹诺酮类药治疗伤寒疗效确切。我院1994～1995年使用氟嗪酸加丁胺卡那霉素治疗伤寒65例,效果满意。报道如下。1 临床资料1.1病例:65例中,男40例,女25例,年龄15～45岁。随机分成两组:治疗组35例,对照组30例。两组年龄、性别、疗程、体温等方面无显著差异性,肾功能均正常。1.2治疗方法:治疗组用氟嗪酸0.2g tid,口服,丁胺卡那霉素0.4g+5％GS250ml静滴,Bid,热退后治疗方案不变。对照组采用氯霉素0.75g+丁胺卡那霉素0.4g+5％GS 250ml静滴,Bid,每3天查WBC1次,热退后氯霉素改用0.5g,tid,口服。两组疗程均为2周,均未用退热药,均予支持治疗。
In recent years, many reports of third-generation quinolone treatment of typhoid fever exact effect. In our hospital from 1994 to 1995, 60 cases of typhoid fever were treated with triflumilazine and amikacin, and the results were satisfactory. Reported as follows. 1 clinical data 1.1 cases: 65 cases, 40 males and 25 females, aged 15 to 45 years. Randomly divided into two groups: treatment group 35 cases, control group 30 cases. Two groups of age, gender, treatment, body temperature and other aspects of no significant difference, normal renal function. 1.2 Treatment: The treatment group withloxacin 0.2g tid, oral, amikacin 0.4g +5% GS250ml intravenous infusion, Bid, thermal treatment program unchanged. Control group with chloramphenicol 0.75g + amikacin 0.4g + 5% GS 250ml intravenous infusion, Bid, WBC1 check every 3 days, hot chloramphenicol to 0.5g, tid, oral. Two courses of treatment were 2 weeks, did not use antipyretics, are to support the treatment.