冶炼工人累积接触砷和吸烟与肺癌关系的病例对照研究

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1982年,作者对3916名于1928~1967年间从事冶炼3个月以上的炼铜工人进行了随访调查。据估计,任何一个工作场所,冶炼工都有三个时期的砷接触。将详细的工作记录与毒物的接触情况相联系,即分别反映出各冶炼工人累积接触砷的程度。通过队列分析,初步发现累积接触砷与肺癌间有明显的剂量效应关系。该队列共收集了108名有吸烟 In 1982, the authors conducted a follow-up survey of 3,916 copper-smelting workers who engaged in smelting for more than three months from 1928 to 1967. It is estimated that any workplace, smelters have three arsenic exposure. Linking detailed records of work with exposure to poisons reflects the extent to which smelters have accumulated exposure to arsenic, respectively. Through the cohort analysis, it was initially found that cumulative exposure to arsenic and lung cancer have obvious dose-response relationship. The queue collected a total of 108 smokers
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