论文部分内容阅读
目的 :观察人工肝支持系统 (ALSS)治疗重型病毒性肝炎的临床疗效。方法 :12例重型病毒性肝炎在综合护肝治疗上加用ALSS治疗。结果 :ALSS治疗后 ,总胆红素从 488 3 0 μmol/L降至 2 94 3 6μmol/L( P <0 0 5 ) ,凝血酶原活动度从 2 6 2 9%提高至 40 97% (P <0 0 5 ) ,总生存率为 5 8 3 % ,早中期生存率 70 %。结论 :ALSS对重型病毒性肝炎肝功能衰竭有明显疗效。对早中期重型肝炎效果较好
Objective: To observe the clinical efficacy of artificial liver support system (ALSS) in the treatment of severe viral hepatitis. Methods: Twelve patients with severe viral hepatitis were treated with ALSS combined with hepatoprotective therapy. Results: The total bilirubin decreased from 488 30 μmol / L to 2 94 36 μmol / L after ALSS treatment (P <0.05), and the activity of prothrombin increased from 26 62% to 40 97% (P < P <0.05). The overall survival rate was 58.3% and the early-mid-term survival rate was 70%. Conclusion: ALSS has obvious curative effect on liver failure of severe viral hepatitis. Early and mid-term effect of severe hepatitis is better