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目的对比分析联合使用米非司酮、米索前列醇、利凡诺羊膜腔注射术后服用益母草胶囊对中期妊娠患者的引产效果。方法选取2013年6月至2014年6月期间收入院的中期妊娠需引产的孕妇共250例为研究对象,随机分为观察、对照两组,每组各125例。观察组孕妇联合应用米非司酮、米索前列醇、利凡诺羊膜腔内注射引产术后服用益母草胶囊治疗,对照组孕妇则口服米非司酮联合阴道后穹窿防止米索前列醇引产,收集两组妊娠终止时间、胎盘残留量、阴道流血量以及药物相关不良反应发生情况。结果治疗结束后观察组妊娠终止时间、胎盘残留量、阴道出血量以及VAS评分方面均显著低于对照组(P<0.05),两组药物相关不良反应发生情况方面对比观察组显著低于对照组(P<0.05)具有统计学意义。结论联合应用利凡诺羊膜腔注射,术后服用益母草胶囊进行中期引产疗效较传统引产方法更为优秀,不良反应少安全有效,值得临床推广应用。
OBJECTIVE: To compare and analyze the induction effect of combined use of mifepristone, misoprostol and rivanol amiodarone in the second trimester of pregnancy. Methods A total of 250 pregnant women who needed induction of labor during the second trimester of pregnancy were recruited from June 2013 to June 2014, and randomly divided into observation and control groups, with 125 cases in each group. Observation group pregnant women combined with mifepristone, misoprostol, rivanol amniotic fluid injection of motherwort after taking induction of motherwort capsules, the control group of pregnant women oral mifepristone combined with vaginal fornix to prevent misoprostol induction of labor, The termination of pregnancy, placental residual volume, vaginal bleeding and drug-related adverse events were collected. Results After treatment, the termination of pregnancy, residual placenta, vaginal bleeding volume and VAS score in the observation group were significantly lower than those in the control group (P <0.05). The two groups were significantly lower than the control group in the incidence of adverse drug reactions (P <0.05) with statistical significance. Conclusions The combined application of Rivanol intracavitary injection, after taking Leonurus capsules for mid-term induction of labor more effective than traditional induction of labor is more effective, less adverse reactions safe and effective, worthy of clinical application.