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目的探讨帕金森病(PD)患者伴发运动并发症的情绪、认知、运动功能。方法 82例原发性PD患者,采用汉密尔顿焦虑量表(HAMA14)和汉密尔顿抑郁量表(HAMD_(24))评价焦虑和抑郁情绪、简易智能状态检查量表(MMSE)和蒙特利尔认知评价量表(MoCA,北京版)评价认知功能,统一帕金森病评价量表第三部分(UPDRSⅢ)和Hoehn-Yahr分级评价病情严重程度,分析PD患者伴发运动并发症的情绪、认知、运动功能变化。结果 82例PD患者中,36例(43.90%)存在运动并发症,与不伴运动并发症的PD患者相比,伴运动并发症的PD患者病程、HAMA_(14)评分、HAMD_(24)评分、UPDRSⅢ评分、Hoehn-Yahr分期明显增高,二组间的差异有统计学意义(P<0.05),而二组的MoCA评分、MMSE评分之间的差异无统计学意义(P>0.05)。结论 PD伴发运动并发症的患者病程长,焦虑抑郁情绪较严重,运动功能较差。
Objective To investigate the emotional, cognitive and motor functions of patients with Parkinson’s disease (PD). Methods Eighty-two patients with primary PD were evaluated for anxiety and depression by using Hamilton Anxiety Scale (HAMA14) and Hamilton Depression Scale (HAMD_ (24)), MMSE and Montreal Cognitive Assessment Scale (MoCA, Beijing) to evaluate the cognitive function, the third part of the Unified Parkinson’s Disease Rating Scale (UPDRS Ⅲ) and the Hoehn-Yahr classification to evaluate the severity of the disease. The emotional, cognitive and motor functions of PD patients with exercise complications Variety. Results Of the 82 PD patients, 36 (43.90%) had motor complications. Compared with those without PD, the duration of HAMA_ (14), HAMD_ (24) , UPDRSⅢscore, and Hoehn-Yahr staging were significantly higher in the two groups (P <0.05). There was no significant difference between the two groups in MoCA score and MMSE score (P> 0.05). Conclusions Patients with PD complicated with motor complications have long course of illness, severe anxiety and depression, and poor motor function.