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目的:了解药物不良反应(ADR)发生的规律和特点,为临床合理用药提供参考。方法:对湖北省潜江市老新镇卫生院2013~2015年上报的389例ADR报告,按患者性别、年龄、药品剂型、种类、ADR累及器官(系统)进行统计分析。结果:发生ADR患者中,男女比例为0.95∶1;抗感染类药物引起的ADR最多,有248例,占50.72%,全身性损害、皮肤系统和消化系统的损伤较为常见,分别为240例(49.08%)、111例(22.70%)、67例(13.70%);药品剂型中,注射剂引发的ADR较多,为250例(51.12%)。结论:ADR在临床药物治疗中比较常见,应全面做好ADR监控和防护工作,为用药安全提供保障。
OBJECTIVE: To understand the regularity and characteristics of adverse drug reaction (ADR) and to provide a reference for clinical rational drug use. Methods: A total of 389 ADR cases reported by Laoxin Township Hospital in Qianjiang City of Hubei Province from 2013 to 2015 were analyzed statistically according to their gender, age, drug dosage form and type, ADR involved organ (system). Results: ADR patients, the ratio of men and women was 0.95:1; anti-infective drugs caused the most ADR, 248 cases, accounting for 50.72%, systemic damage, skin and digestive system damage are more common, were 240 cases 49.08%), 111 cases (22.70%) and 67 cases (13.70%). There were 250 cases (51.12%) of ADR caused by injection in the drug dosage forms. Conclusion: ADR is more common in clinical drug treatment. ADR monitoring and prevention should be fully carried out so as to provide security for drug safety.