论文部分内容阅读
头孢菌素(以下简称头孢)是一类临床价值较高的抗生素,分子结构中均具有7-氨基头孢霉烷酸(7ACA)母核。其特点为抗菌谱广,杀菌作用强,对革兰阳性和阴性菌、需氧菌或厌氧菌均有强大的抗菌作用;对细菌产生的β-内酰胺酶,较大多数半合成青霉素稳定;毒性低,副作用少,具有类似青霉素的良好属性,且过敏反应发生率比青霉素低,临床应用以来耐药菌株的增加不明显,这些都为临床治疗提供
Cephalosporins (hereinafter referred to as cephalosporins) is a class of high clinical value of antibiotics, molecular structure with 7-aminocephalosporanic acid (7ACA) mother nucleus. It is characterized by broad antibacterial spectrum, strong bactericidal effect on Gram-positive and -negative bacteria, aerobic bacteria or anaerobic bacteria have a strong antibacterial effect; the bacteria produce β-lactamase, the majority of semi-synthetic penicillin stability ; Low toxicity, fewer side effects, with good attributes similar to penicillin, and the incidence of allergic reactions than penicillin low resistance strains have not increased significantly since the clinical application, these are provided for clinical treatment