论文部分内容阅读
Kaposi肉瘤(Kaposi’s sarcoma,KS)、部分多中心血管滤泡淋巴增生症(multi-centric castle-man’s disease,MCD)和原发性渗出性淋巴瘤(primary effusion lymphoma,PEL)等和AIDS相关恶性肿瘤的发生与人类疱疹病毒8型(Human Herpesvirus-8,HHV-8)密切相关[1]。HHV-8是一种重要的具有高度致癌性的人类肿瘤病毒,在HHV-8相关的疾病中,KS最为多见。研究表明,在Kaposi肉瘤患者的瘤组织中,HHV-8DNA检出率为80%~100%[2]。随着实时荧光定量PCR技术的发展,从定量角度分析和探讨HHV-8病毒
Kaposi’s sarcoma (KS), partial multi-centric castle-man’s disease (MCD) and primary effusion lymphoma (PEL) Tumor occurrence is closely related to Human Herpesvirus-8 (HHV-8) [1]. HHV-8 is an important, highly oncogenic human oncolytic virus that is most commonly found in HHV-8-related diseases. Studies have shown that the detection rate of HHV-8 DNA in the tumor tissue of Kaposi’s sarcoma is 80% ~ 100% [2]. With the development of real-time fluorescence quantitative PCR technology, quantitative analysis of HHV-8 virus