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本文用双抗体夹心ＥＬＩＳＡ法检测了３５例鼻咽癌患者放疗前后血清ｓＩＬ—２Ｒ水平。结果显示：鼻咽癌患者放疗前血清ｓＩＬ—２Ｒ水平显著高于正常人（Ｐ＜０．００１），且随病情进展而升高；放疗后血清ｓＩＬ—２Ｒ水平较放疗前显著降低（Ｐ＜０．００１）；Ⅲ－Ⅳ期患者放疗后ｓＩＬ—２Ｒ水平＞１０００ｕ／ｍｌ的死亡率（３／５，６０％）高于放疗后ｓＩＬ—２Ｒ水平＜１０００ｕ／ｍｌ（１／１０，１０％）。结果表明鼻咽癌患者血清ｓＩＬ—２Ｒ水平与肿瘤的消长密切相关，血清ｓＩＬ—２Ｒ有可能作为疗效和预后判断的一种重要监测指标。
In this study, 35 cases of nasopharyngeal carcinoma patients before and after radiotherapy with serum sIL-2R levels were detected by sandwich ELISA. The results showed that the level of sIL-2R in patients with nasopharyngeal carcinoma before radiotherapy was significantly higher than that in normal people (P <0.001), and increased with the progression of the disease. The serum sIL-2R level after radiotherapy was significantly lower than that before radiotherapy (P < 0.001). The mortality of sIL-2R> 1000u / ml after radiotherapy in patients with stage III-IV was higher than that of sIL-2R <1000u / ml after radiotherapy (1/10 and 10% ). The results show that serum sIL-2R levels in patients with nasopharyngeal carcinoma is closely related to tumor growth and decline, serum sIL-2R may be used as an important monitoring indicators of efficacy and prognosis.