非高密度脂蛋白胆固醇与冠心病的相关性研究

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目的探讨非高密度脂蛋白胆固醇(non-HDL-C)与冠心病的关系。方法对连续372例冠脉造影患者的血脂及冠脉造影结果回顾性分析。冠脉造影阴性114例为对照组,冠脉造影阳性258例为冠心病组,冠心病组根据冠脉病变支数分为单支病变组(104例)和双支及三支病变组(154例),对以上各组的血脂及non-HDL-C结果进行比较。结果①与冠脉造影阴性组比较,冠脉造影阳性组non-HDL-C水平明显增高。②在冠脉造影阳性组,non-HDL-C水平随病变支数增加而上升。结论 non-HDL-C与冠状动脉粥样硬化病变关系密切,控制non-HDL-C在冠心病的防治中有重要意义。 Objective To investigate the relationship between non-high density lipoprotein cholesterol (non-HDL-C) and coronary heart disease. Methods The results of lipids and coronary angiography in 372 consecutive coronary angiography patients were retrospectively analyzed. One hundred and eighteen patients with coronary artery disease were enrolled in this study. One hundred and eighteen patients with coronary artery disease were enrolled in the study. Cases), the above groups of blood lipids and non-HDL-C results were compared. Results ① Compared with the coronary angiography negative group, the non-HDL-C levels in the positive coronary angiography group were significantly higher. ② In coronary angiography positive group, the level of non-HDL-C increased with the lesion count increased. Conclusion Non-HDL-C is closely related to coronary atherosclerosis. It is important to control non-HDL-C in the prevention and treatment of coronary heart disease.
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