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目的通过探讨胎膜早破与宫内感染和新生儿发病率的相关性,旨在为预防宫内感染、提高新生儿出生质量提供理论依据。方法分娩的胎膜早破产妇67例作为研究组,再选择同期分娩的正常产妇67例作为对照组,对患者临床资料进行统计分析,记录两组产妇宫内感染率、新生儿肺炎率、新生儿窘迫率及高胆红素血症率,同时应用实验室检查羊水残余量、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)及肿瘤坏死因子-α(TNF-α)水平。结果研究组患者宫内感染率、新生儿肺炎率、新生儿窘迫率及高胆红素血症率均显著高于对照组,且羊水残余量、IL-6、IL-8及TNF-α水平两组差异有统计学意义(P<0.05)。结论胎膜早破与宫内感染和新生儿发病率密切相关。
Objective To explore the correlation between premature rupture of membranes and intrauterine infection and neonatal morbidity and to provide a theoretical basis for preventing intrauterine infection and improving the birth quality of newborns. Methods 67 cases of premature rupture of membranes of maternal childbirth were selected as the study group, and 67 normal maternal births were selected as the control group. The clinical data of the patients were statistically analyzed. The intrauterine infection rate, neonatal pneumonia rate, Child distress rate and hyperbilirubinemia rate. At the same time, the amount of amniotic fluid residual, interleukin-6 (IL-6), interleukin-8 (IL-8) and tumor necrosis factor- -α) levels. Results The intrauterine infection rate, neonatal pneumonia rate, neonatal distress rate and hyperbilirubinemia rate in the study group were significantly higher than those in the control group, and the amniotic fluid residual levels, IL-6, IL-8 and TNF-α levels The difference between the two groups was statistically significant (P <0.05). Conclusion Premature rupture of membranes is closely related to intrauterine infection and neonatal morbidity.