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目的研究急性心肌梗死(AMI)时影响冠脉侧支循环(CCC)形成的因素。方法共入选142例就诊我院的首次AMI患者,均在AMI发作1 d内行冠状动脉造影术(CAG),依照Rentrop侧支循环分级,分为侧支循环良好组(良好组:侧支循环Ⅱ、Ⅲ级)和侧支循环不良组(不良组:侧支循环0、Ⅰ级),将两组患者的临床资料和冠脉造影资料进行对比分析。结果冠脉侧支循环形成与糖尿病呈负相关,与梗死前心绞痛病程(>3个月)及冠脉病变支数呈正相关,而与年龄、性别、吸烟史、血脂水平、高血压病等无关。结论梗死前心绞痛病程(>3个月)、冠脉病变支数是AMI患者形成侧支循环的有利因素,糖尿病不利于侧支循环形成。
Objective To study the factors influencing the formation of coronary collateral circulation (AMC) in acute myocardial infarction (AMI). Methods The first AMI patients in our hospital were enrolled in this study. All patients underwent coronary angiography (CAG) within 1 day of onset of AMI. According to Rentrop collateral circulation classification, they were divided into two groups: good collateral circulation group (good group: collateral circulation Ⅱ , Grade Ⅲ) and poor collateral circulation group (bad group: collateral circulation 0, Ⅰ grade), the clinical data of two groups and coronary angiography data were analyzed. Results The formation of coronary collateral circulation was negatively correlated with diabetes mellitus, which was positively correlated with the course of angina (> 3 months) and the number of coronary artery lesions before infarction, but not with age, gender, smoking history, blood lipid level, hypertension, etc. . Conclusions The duration of pre-infarction angina (> 3 months) and the number of coronary lesions are favorable factors for the formation of collateral circulation in patients with AMI. Diabetes is not conducive to the formation of collateral circulation.