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目的:观察比较完全胸腔镜手术与传统开放肺叶切除术治疗非小细胞肺癌的临床效果。方法:选择非小细胞肺癌120例,随机分为观察组和对照组各60例。观察组采用完全胸腔镜肺叶切除术治疗,对照组采用传统开放肺叶切除术治疗,比较两组手术时间、术中出血量、术后置管时间、住院时间、术后并发症发生情况,以及视觉模拟评分(VAS)和血清C-反应蛋白(CRP)水平。结果:观察组术中出血量、术后置管时间均显著少于或短于对照组(P<0.05);两组手术时间、住院时间、术后并发症发生情况比较,差异不显著(P>0.05);观察组术后第1天、第3天的VAS分值均显著低于对照组(P<0.05);两组术后CRP水平均显著或非常显著高于术前(P<0.05,P<0.01),且观察组术后CRP水平显著低于对照组(P<0.05)。结论:完全胸腔镜手术治疗非小细胞肺癌效果与开放肺叶切除术相当,但出血量少、患者疼痛程度轻。
Objective: To observe the clinical effect of complete thoracoscopic surgery and traditional open lobectomy for non-small cell lung cancer. Methods: 120 cases of non-small cell lung cancer were randomly divided into observation group and control group, 60 cases each. The observation group was treated by complete thoracoscopic lobectomy. The control group was treated by open lobectomy. The operation time, intraoperative blood loss, postoperative catheterization time, hospital stay, postoperative complications, Simulated scores (VAS) and serum C-reactive protein (CRP) levels. Results: The intraoperative blood loss and postoperative catheterization time in observation group were significantly shorter than those in control group (P <0.05). There was no significant difference in operative time, hospitalization time and postoperative complication > 0.05). The VAS scores of the observation group were significantly lower than those of the control group on the first day and the third day after operation (P <0.05). CRP levels in both groups were significantly or very significantly higher than those before operation (P <0.05) , P <0.01), and the postoperative CRP level in the observation group was significantly lower than that in the control group (P <0.05). Conclusions: The effect of total thoracoscopic surgery for non-small cell lung cancer is comparable to that of open lobectomy, but the amount of bleeding is low and the patient is less painful.