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目的:探讨运用胸腔镜治疗<3个月婴儿先天性肺气道畸形(congenital pulmonary airway malformation，CPAM)的可行性。方法:收集2017年3月至2020年7月经胸腔镜治疗的13例CPAM患儿(<3个月婴儿)的临床资料，对其手术治疗及术后恢复情况进行总结分析。其中，男7例，女6例；手术年龄范围为0.67～2.87个月；体重范围为2.5～6.4 kg。12例于孕期发现病变，3例早产。结果:所有患儿的手术均在胸腔镜下完成，无中转开胸病例；其中11例行肺叶切除术，2例行肺叶切除+肺不规则切除术。手术时间范围为45～200 min，中位数为115 min；术中出血量范围为5～20 ml，中位数为10 ml。术后引流管留置时间范围为2～10 d，中位数为3 d；术后住院时间范围为4～12 d，中位数为6 d。术后病理学检查结果：1型6例、2型4例、3型2例和4型1例。术后出现漏气1例，延长带管时间后漏气消失，无出血、支气管胸膜瘘、肺不张等术后并发症。随访时间范围为4个月至3年，所有患儿均恢复良好。复查胸部CT均未见残余病灶，可见肺部炎症消散、患侧胸腔无残腔。结论:对于有症状的<3个月的CPAM患儿应尽早行手术治疗；随着微创技术和麻醉管理水平的提高，胸腔镜运用于治疗该类患儿是相对安全有效的。“,”Objective:To explore the feasibility of thoracoscopy for congenital pulmonary airway malformation (CPAM) in infants aged under 3 months.Methods:From March 2017 to July 2020, clinical data were reviewed for 13 CPAM children aged under 3 months undergoing thoracoscopy. Surgical approaches and postoperative recovery were summarized. There were 7 boys and 6 girls with an operative age of (0.67-2.87) months and body weight ranged from 2.5 to 6.4 kg. Twelve cases revealed pathological changes during pregnancy and three cases were premature.Results:All operations were performed under thoracoscope and there was no conversion into thoracotomy. There were lobectomy (n=11) and lobectomy plus irregular lung resection (n=2). The median operative duration was 115(45-200) min, the median volume of intraoperative blood loss 10(5-20) ml, the median postoperative indwelling time of drainage tube 3(2-10) days and the median postoperative hospital stay 6(4-12) days. Postoperative pathological examination indicated that clinical types were Ⅰ (n=6), Ⅱ (n=4), Ⅲ (n=2) and Ⅳ (n=1). One case of postoperative air leakage disappeared after prolonging tubing time. There were no postoperative complications such as bleeding, bronchopleural fistula or atelectasis. During a follow-up period of 4 to 36 months, all patients recovered well. No residual lesions were found on chest computed tomography (CT), pulmonary inflammation dissipated and no residual cavity was found at the affected side.Conclusions:Surgery should be performed as early as possible for symptomatic CPAM children aged under 3 months. With the improvement of mini-invasive technology and anesthesia management level, thoracoscopy is relatively safe and effective.