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目的：探讨观察瑞芬太尼复合异丙酚在临床手术中的应用价值。方法选取我院收治的择期手术患者1662例，随机分成观察组和对照组，观察组采取瑞芬太尼复合异丙酚进行全凭静脉麻醉，对照组采取静吸复合麻醉，比较两组麻醉效果。结果观察组和对照组诱导前、插管前、插管中、术中和术毕的 MAP及 HR指标比较，差异具有显著性，有统计学意义（P＜0.05）。观察组呼吸恢复时间、清醒时间、拔管时间、定向力恢复时间均少于对照组，差异具有显著性，有统计学意义（P＜0.05）。结论对择期手术患者采用瑞芬太尼复合异丙酚进行麻醉，麻醉效果明确、见效快、剂量小、作用时间短且安全可靠。“,”Objective To explore observation,Propofol-remifentanil application value in clinical surgery. Methods Select patients undergoing elective surgery of our hospital 1662 cases,randomly divided into observation group and control group,the observation group of preoperative Propofol-remifentanil was taken to al by intravenous anesthesia, control group before taking static absorption compound anesthesia,compared two groups of narcotic ef ect. Results Observation group and control group before the induction and intubation,intubation before,during or after the MAP and HR of index comparison,has a significant dif erence was statistical y significant (P<0.05).Observation group breathing recovery time,waking time,extubation time,directional force recovery time is less than the control group,with significant dif erence,there is statistical significance (P<0.05). Conclusion For patients undergoing elective surgery, Propofol-remifentanil anesthesia, anesthesia ef ect clear, quick ef ect, low dosage, short action time and safe and reliable.