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目的探究高危型人乳头瘤病毒(human papillomavirus,HPV)检测联合宫颈液基细胞学检查在宫颈癌中的作用。方法收集就诊于我院体检妇科进行妇科检查,且进行HPV检测及TCT检查的的患者512例,整理并分析HPV检测与TCT检查的结果与宫颈癌的关系,从而得出二者在宫颈癌筛查中的作用。结果联合检测对于宫颈病变诊断的灵敏度、特异性、阳性预测值、阴性预测值及诊断符合率均高于单一检测,差异有统计学意义(P<0.05)。结论在宫颈癌筛查中,HPV检测的灵敏性高,特异性低,TCT检查的特异性高,灵敏性低,二者联合检查可提高宫颈癌筛查水平,优于二者单一检测。
Objective To explore the role of high-risk human papillomavirus (HPV) detection combined with cervical liquid-based cytology in cervical cancer. Methods A total of 512 patients with gynecological examination in our gynecological hospital for gynecological examination and HPV testing and TCT examination were collected and analyzed. The results of HPV test and TCT examination and cervical cancer were collected and analyzed. Check the role. Results The sensitivity, specificity, positive predictive value, negative predictive value and diagnostic coincidence rate of combined detection for cervical lesions were higher than those of single detection, the difference was statistically significant (P <0.05). Conclusion In the screening of cervical cancer, HPV detection has high sensitivity, low specificity, high specificity and low sensitivity of TCT. The combination of the two can improve the screening of cervical cancer, which is better than the single detection of both.